The SinCMat web interface essentially includes 3 sections: the webtool, which enables users to apply SinCMat algorithm to their specific target cell, the database which allows the users to browse all maturation TF evidences collected from the literature, and finally, an atlas section that provides maturation TFs for a series of mouse and human celltypes.
The webtool panel provides a very intuitive interface to predict maturation TF from their own single-cell RNA-seq dataset.
The database section allows user to browse literature evidences of maturation TFs collected, classified by systems. The search area enables users to search in the database based on the TFs, celltypes, species and types of experiment (of note, “up-regulated” TFs correspond to overexpressed and/or activated TFs). To retrieve the original article of a given evidence, users can click on the URL link or search with the Pubmed ID.
To achieve the batch download of the whole database, users can go to the Download section.
On the left part of the panel, users can select a celltype of interest. The results are displayed as a table on the right part of the panel. The 2 first columns represent the 5 predicted pairs of ITF/STF. The 2 next columns indicate the users if the TFs predicted were already experimentally validated (see Database section).
To achieve the batch download of the predictions for the MCA or TS, users can go to the Download section.
For more information, please refer to our Terms and Conditions at the following link: Terms and conditions